Human Whole Genome Sequencing (WGS)
Human whole genome sequencing enables researchers to catalog the genetic constitution of individuals and capture all the variants present in a single assay. It is applied to the study of cancer and a variety of diseases, as well as human population evolution studies and pharmacogenomics.
Overview of Service:
State-of-the-art NGS technologies:
350 bp insert DNA libraries
HiSeq X platform, paired-end 150 bp
Highest data quality:We guarantee a Q30 score ≥ 80%, exceeding Illumina’s official guarantee of ≥75%.
Bioinformatics analysis:
Data quality control
Alignment with reference genome, statistics of sequencing depth and coverage
SNP/InDel, SV and CNV calling, annotation and statistics
Somatic SNP/InDel, SV and CNV calling, annotation and statistics for tumor-normal paired samples.
Fast turnaround time:
20 working days after verification of sample quality (without data analysis)
Additional 8 working days for data analysis
Recommended Sequencing Depth
For tumor tissues: 50×, adjacent normal tissues and blood 30×
For rare diseases: 30~50x